Description
Product Characteristics:
Aliases: Actin related protein 1 antibody, Actin RPV antibody, Actin-RPV antibody, ACTR 1A antibody, Actr1a antibody, ACTZ_HUMAN antibody, Alpha centractin antibody, Alpha-centractin antibody, ARP 1 antibody, ARP1 actin related protein 1 homolog A antibody, ARP1 actin related protein 1 homolog A centractin alpha antibody, ARP1 antibody, ARP1 yeast homolog A antibody, Centractin alpha antibody, Centractin antibody, Centrosome associated actin homolog antibody, Centrosome-associated actin homolog antibody, CTRN 1 antibody, CTRN1 antibody, FLJ52695 antibody, FLJ52800 antibody, FLJ55002 antibody
Target Information: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]